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chenodeoxycholic acid 24 acyl β d glucuronide  (Toronto Research Chemicals)


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    Structured Review

    Toronto Research Chemicals chenodeoxycholic acid 24 acyl β d glucuronide
    Chenodeoxycholic Acid 24 Acyl β D Glucuronide, supplied by Toronto Research Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/chenodeoxycholic+acid+24+acyl+%CE%B2+d+glucuronide/Chenodeoxycholic+Acid+24-Acyl-Beta-D-glucuronide/pm41991640-53-33-49
    Average 94 stars, based on 1 article reviews
    chenodeoxycholic acid 24 acyl β d glucuronide - by Bioz Stars, 2026-09
    94/100 stars

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    Article Title: Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes.
    Article Snippet: Along with the prevalence of drug combination therapies, an increasing number of cases about drug-drug interactions (DDI) have been reported, which has drawn a lot of attention due to the potential toxicity and/or therapeutic failure.. Pharmacokinetic AC CE PT ED M AN US CR IP T

    Article Title: Identification of the human Cytochrome P450 enzymes (P450s) responsible for metabolizing infigratinib to its pharmacologically active Metabolites, BHS697, and CQM157, and assessment of their in vitro inhibition of P450s and UDP-glucuronosyltransferases (UGTs).
    Article Snippet: Infigratinib, an oral FGFR inhibitor for advanced cholangiocarcinoma, yielded two active metabolites, BHS697 and CQM157, with similar receptor affinity.. Our study characterized P450s that are responsible for the metabolism of infigratinib to its two major active metabolites, BHS697 and CQM157.. In vitro inhibition of P450s and UGTs by infigratinib, BHS697 or CQM157 was further investigated.

    Article Title: Biotransformation of Penindolone, an Influenza A Virus Inhibitor.
    Article Snippet: Dextromethorphan, midazolam, 4-hydroxymephenytoin, 1-hydroxymidazolam, chenodeoxycholic acid 24-acyl-β-D-glucuronide, serotonin-β-D-glucuronide and 3′-azido3′-deoxythymidine-β-D-glucuronide were acquired from Toronto Research Chemicals (Toronto, Canada).

    Article Title: Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions.
    Article Snippet: Accepted Manuscript Identification and characterization of in vitro inhibitors against UDPglucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursidrug interactions Jung Bae Park, Doyun Kim, Jee Sun Min, Su Jeong, Doo-Yeoun Cho, Yu Fen Zheng, Kee Dong Yoon, Soo Kyung Bae PII: S0278-6915(18)30503-9 DOI: 10.1016/j.fct.2018.07.058 Reference: FCT 9943 To appear in: Food and Chemical Toxicology Received Date: 30 March 2018 Revised Date: 27 June 2018 Accepted Date: 30 July 2018 Please cite this article as: Park, J.B., Kim, D., Min, J.S., Jeong, S., Cho, D.-Y., Zheng, Y.F., Yoon, K.D., Bae, S.K., Identification and characterization of in vitro inhibitors against UDP-glucuronosyltransferase 1A1 in uva-ursi extracts and evaluation of in vivo uva-ursi-drug interactions, Food and Chemical Toxicology (2018), doi: 10.1016/j.fct.2018.07.058.. This is a PDF file of an unedited manuscript that has been accepted for publication.. As a service to our customers we are providing this early version of the manuscript.

    Article Title: Contributions of UDP-Glucuronosyltransferases to Human Hepatic and Intestinal Metabolism of Ticagrelor and Inhibition of UGTs and Cytochrome P450 Enzymes by Ticagrelor and its Glucuronidated Metabolite
    Article Snippet: Reference standard of ticagrelor (purity 95.0%), 7-Ethyl-10-hydroxy-camptothecin (SN-38) glucuronide (purity 97%), chenodeoxycholic acid 24-acyl-β-D-glucuronide (purity 96%), N-Acetyl serotonin β-D-glucuronide (purity 97%), mycophenolic acid β-D-glucuronide (purity 96%), 3′-azide-3′-deoxythymidine β-D-glucuronide sodium salt (purity 97%), bupropion (purity 98%), hydroxy bupropion (purity >98%), amodiaquine (purity >95%), N-Desethyl amodiaquine hydrochloride (purity >95%), 4′-hydroxylation diclofenac (purity >95%), S-mephenytoin, S - 4 - hydroxy mephenytoin (purity >98%), dextromethorphan (purity >95%), dextrorphan tartrate salt (purity >98%), and furafylline (purity >95%, internal standard) were purchased from Toronto Research Chemicals (Toronto, ON, Canada).

    Article Title: Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug–Drug Interaction in Healthy Volunteers
    Article Snippet: Chenodeoxycholic acid-24-acyl-β-D-glucuronide (CDCA-24-G) was purchased from Toronto Research Chemicals (Toronto, Canada).

    Article Title: Cross-species metabolic characterization of eutylone and mechanism-based inhibition of CYP2D6 and CYP2B6 with drug interaction implications.
    Article Snippet: Acetaminophen, 7-hydroxycoumarin, bupropion, hydroxybupropion, amodiaquine, N-desethylamodiaquine hydrochloride, diclofenac, 4ʹ-hydroxydiclofenac, (S)-mephenytoin, 4ʹhydroxymephenytoin, bufuralol hydrochloride, 1ʹ-hydroxybufuralol, 1ʹ- ACCEPTED MANUSCRIPT AR TIC LE IN PR ES S ARTICLE IN PRESS hydroxybufuralol-d9, SN-38, SN-38 glucuronide, chenodeoxycholic acid, chenodeoxycholic acid 24-acyl-β-D-glucuronide, N-acetyl-serotonin β-Dglucuronide, mycophenolic acid, mycophenolic acid β-D-glucuronide, and propofol β-D-glucuronide were supplied by Toronto Research Chemicals (Toronto, ON, Canada).



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